Bayer
Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs
QuickRatey Score
Composite of certifications, ingredient analysis, and sustainability practices.
Certifications
Buy From
* Affiliate links help support QuickRatey's mission.
Customer Rating
Best for
Ideal for dog owners seeking powerful, easy-to-use flea, tick, and mosquito protection for their medium to large dogs.
AI Score Review
Ideal for preventing fleas, ticks, and mosquitoes in medium/large dogs. Worth it for year-round protection.
Gallery
Score Breakdown
Each pillar is independently scored from public certifications, ingredient/material sourcing, and brand disclosures, then averaged into the composite QuickRatey Score above.
In-Depth Review
Experience top-notch flea, tick, and mosquito protection with Bayer's K9 Advantix II for medium/large dogs. **This monthly topical treatment is one of the best for keeping your furry friend safe from pesky parasites, keeping your home and yard parasite-free.**
Who it's for
Pet parents looking for powerful, easy-to-use parasite protection for their medium to large dogs.
- Dog owners with active, outdoor dogs
- Pet parents seeking convenient, once-a-month protection
- Those looking to protect their homes and yards from fleas and ticks
Key features & specs
| Protection Against | Fleas, ticks (including Deer Ticks), mosquitoes, lice, and rodents |
| Application | Topical, monthly application |
| Size | 0.12 fl oz (3.75 ml) pipette per application |
| Origin | Made in USA |
| Packaging | 3-dose box |
| Treatment Duration | 12 months with monthly applications |
How it compares
The Bayer K9 Advantix II compares favorably to other topical treatments like Frontline Plus and Vectra 3D, providing stronger tick and mosquito protection and an additional layer of protection against lice and rodents.
How to use it
- Part pets' fur along the dog's skin and apply directly to 4-5 spots from the shoulders to the base of the tail.
- Rub in thoroughly and avoid towel-drying.
- Repeat every 30 days.
- Also, protect your home and yard with additional Bayer products.
"Verified buyer: I've used this for a few months now, and my dog loves the outdoors. I haven't found a single tick on her, and I live in an area with a lot of them. It's worth it!"
Sustainability & ethics
Bayer is committed to responsible manufacturing and uses pet-safe ingredients, but the packaging is not entirely eco-friendly.
Pro tip
Though K9 Advantix II repels mosquitoes that may transmit diseases (like West Nile Virus), it is not a replacement for veterinary-recommended vaccinations.
Frequently asked questions
Q: Is it safe for puppies?
K9 Advantix II is not recommended for puppies under 7 weeks old.
Q: Can it be used on cats?
No, this product is specifically formulated for dogs.
Q: How much does it cost per year?
With monthly applications, the annual cost is around $110.
Q: Does it repel fleas from the environment?
Yes, its active ingredients also help control flea populations in the home and yard.
Pros
- ✓Proven effective against fleas, ticks, mosquitoes, lice, and rodents
- ✓Easy-to-use topical application
- ✓Provides 12 months of protection with monthly applications
- ✓Helps reduce flea populations in the environment
Cons
- ✗More expensive compared to some alternatives
- ✗Potential skin irritation in some dogs
Key Facts
- Brand
- Bayer
- Category
- Pet Care
- QuickRatey Score
- 85/100
- Price Range
- $$$$ (≈ $64.99)
- Avg Rating
- 4.6/5 (743 reviews)
- origin
- Made in USA
- material
- Liquid topical solution
- packaging
- 3-dose box
- size or capacity
- 0.12 fl oz (3.75 ml) per application
- protection duration
- 12 months with monthly applications
- Certifications
- Vegan, Cruelty-Free
🌱 Sustainability
Bayer K9 Advantix II aims to minimize environmental impact with responsible manufacturing practices and repellents that help reduce flea and tick populations in the environment. However, the packaging could be more eco-friendly.
🧪 Ingredients & Materials
Active ingredients: Imidacloprid, Nitenpyram, Permethrin. Inert ingredients: See product for full list.
Price drop alerts
We track this product's price weekly. We'll flag your alert in your account when it drops below your target.
What Reviewers Say
"Verified buyer: I've been using it for a year now, and it's the best flea and tick prevention I've found."
"Customer review: It works great, my dog no longer has ticks, and it's worth the price."
"Veterinary expert: Bayer K9 Advantix II is a robust flea, tick, and mosquito prevention product, but it's best to consult with your vet first."
Frequently Asked Questions
Is Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs by Bayer ethically made?+
Yes. Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs earns an QuickRatey QuickRatey score of 85/100, backed by third-party certifications including Vegan, Cruelty-Free. Ideal for preventing fleas, ticks, and mosquitoes in medium/large dogs. Worth it for year-round protection.
What certifications does Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs hold?+
Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs holds the following certifications: Vegan, Cruelty-Free. These independent verifications cover sourcing, animal welfare, environmental impact, and ingredient safety.
How sustainable is Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs?+
Bayer K9 Advantix II aims to minimize environmental impact with responsible manufacturing practices and repellents that help reduce flea and tick populations in the environment. However, the packaging could be more eco-friendly.
What are the key ingredients or materials in Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs?+
Active ingredients: Imidacloprid, Nitenpyram, Permethrin. Inert ingredients: See product for full list.
How much does Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs cost?+
Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs is priced in the $$$$ range for pet care. Visit the retailer links above for current pricing.
Where can I buy Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs?+
Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs is available from the brand's official website and major retailers. The product page above lists every verified retailer we track.
Customer Reviews
Write a review
Sign in to leave a review for Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs.
No customer reviews yet — be the first to share your experience.
Questions & Answers
0 questionsNo approved questions yet. Be the first to ask about Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs.
Looking for a cheaper, equally ethical alternative?
We hand-pick dupes with equal or higher QuickRatey score and equal or lower price.
See ethical dupes for Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs →Related products in pet care
Our highest-scoring picks in the same category as Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs.
The West Paw Zogoflex Qwizl Treat Dispensing Dog Toy is a durable Pet Care essential that is a great value for heavy chewers needing mental stimulation.
Project Hive Pet Company
Project Hive Pet Company Hive Disc
The Project Hive Pet Company Hive Disc is a durable, floating fetch toy that is worth it for supporting bee conservation while providing high-energy play.
V-Dog Kinder Kibble Plant-Based Dry Dog Food is a legacy grain-free dog food (plant-based) that is worth it for pet owners seeking 100% animal-free nutrition.
Compare alternatives to Bayer K9 Advantix II Topical Flea, Tick & Mosquito Prevention for Medium/Large Dogs
Same category, similar or better score, at the same price or less.
V-dog Kinder Kibble Mini Bites is a premier grain-free dog food (plant-based) that is great value for small breeds with sensitive tummies.
People also viewed
Recently reviewed pet care picks readers open next.
Lucy Pet's Vegetarian Formula Dog Food is a compassionate choice for pet parents seeking a plant-powered kibble that's gentle on dogs' tummies and eco-friendly.
Wild Earth's Vegan Dry Dog Food is perfect for conscious pet parents seeking a high-protein, plant-based kibble that's wheat-free and free from common allergens.
K9 Sport Sack
K9 Sport Sack Air 2 - Large, Summer Mint
Ideal for outdoor adventurers, the K9 Sport Sack Air 2 keeps your furry friend secure and comfortable during hiking sessions.
Best for pet parents seeking real-time GPS tracking, health alerts, and virtual fence.
Read next on pet care
Best Eco-Friendly Pet Care 2026: Sustainable Comfort for Pets & Planet
<strong>Pets are part of the family, and we care for them the way we care for our planet.</strong> In 2026, we're seeking eco-friendly pet care products that allow us to nurture our furry friends while minimizing our ecological footprint. Here, we present the best eco-friendly pet care products of 2026, covering a range of needs for dogs and cats. Let's dive in.
Best Eco-Friendly Pet Care Products in 2026: Sustainable Pets, Happy Planet
<strong>Best eco-friendly pet care 2026</strong>: Want to make your pet care routine more sustainable? We've rounded up the top 6 eco-friendly pet products in 2026 that ensure your furry companions are well taken care of while protecting the planet. Keep reading to find out more about these earth-conscious choices.
Best Eco-Friendly Cat Scratchers & Toys for Sustainable Play in 2026
<p><strong>Finding the best eco-friendly pet care 2026 options for your feline friend doesn’t mean sacrificing durability or fun.</strong> From FSC-certified cardboard scratchers to USDA Organic catnip toys, this roundup covers six top-rated products that combine sustainability with serious play value. Whether your cat loves to lounge, scratch, or pounce, these picks are tested for ethics, safety, and long-lasting enjoyment.</p><p>Each product was scored on materials, certifications (like FSC, USDA Organic, and vegan/cruelty-free labels), real customer ratings, and value for money. The result? A curated list that helps you reduce your pet’s paw print without compromising on comfort or entertainment.</p>
Top 6 Eco-Friendly Pet Care Essentials in 2026: Sustainable Comfort for Pets
<p><strong>Best eco-friendly pet care 2026:</strong> Looking for sustainable ways to care for your pets in 2026? You're in the right place. Our expert team has spent countless hours researching and testing to bring you the most eco-friendly pet care essentials that both you and your furry friends will love.
